Iodine Deficiency Disorders Continue to be a Problem in the Asia Pacific Region

Authors

  • Creswell J. Eastman Professor of Medicine, The Sydney Medical School, University of Sydney, Australia Vice Chairman and Regional Coordinator, Asia Pacific Region, International Council for the Control of Iodine Deficiency Disorders (ICCIDD) Principal, The Sydney Thyroid Clinic, Westmead Specialist Centre, New South Wales, Australia

Abstract

Iodine deficiency disorders (IDD) due to inadequate dietary iodine is one of the major non-communicable diseases yet to be eliminated from our world, particularly in the Asia Pacific region.  There has been remarkable progress in reducing iodine deficiency over the past two decades, with 50 more countries declaring successful elimination mainly due to effective implementation of universal salt iodization (USI) programs. The most devastating—but often the least visible—effect of IDD is damage to the central nervous system, causing a spectrum of impairment from mild loss of intelligence quotient (IQ), to severe, irreversible brain damage called neurological cretinism.

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References

Andersson M, Karumbunathan V, Zimmermann MB. Global iodine status in 2011 and trends over the past decade. J Nutr 2012;142(4):744-50.

World Health Organization. WHA 58.24 Sustaining the elimination of iodine deficiency disorders. In: Fifty-Eighth World Health Assembly Resolutions and Decisions Annex WHA58/2005/REC/1. Geneva: World Health Organization, 2005. http://apps.who.int/gb/ ebwha/pdf_files/WHA58-REC1/english/A58_2005_REC1-en.pdf.

Li M, Eastman CJ. The changing epidemiology of iodine deficiency. Nat Rev Endocrinol 2012;8(7):434-40.

Zimmermann MB, Andersson M. Assessment of iodine nutrition in populations: Past, present and future. Nutr Rev 2012;70(10):553-70.

Hetzel BS. Iodine deficiency disorders (IDD) and their eradication. Lancet 1983;2(8359):1126-9.

Halpern JP, Boyages SC, Maberly GF et al. The neurology of endemic cretinism. A study of two endemias. Brain 1991;114(Pt 2):825-41.

Boyages SC, Halpern JP, Maberly GF et al. A comparative study of neurological and myxedematous endemic cretinism in western China. J Clin Endocrinol Metab 1988;67(6):1262-71.

Qian M, Wang D, Watkins WE et al. The effects of iodine on intelligence in children: A meta-analysis of studies conducted in China. Asia Pac J Clin Nutr 2005;14(1):32-42.

Walker SP, Wachs TD, Gardner JM et al. Child development: Risk factors for adverse outcomes in developing countries. Lancet 2007;369(9556):145-57.

Horton S, Mannar V, Wesley A. Best Practice Paper: Food fortification with iron and iodine. Denmark: Copenhagen Consensus Centre, 2008. http://www.copenhagenconsensus.com/Default.aspx?ID=1303

World Health Organization. Assessment of iodine deficiency disorders and monitoring their elimination: A guide for programme managers. 3rd ed. Geneva: World Health Organization, 2007. http://whqlibdoc.who.int/publications/2007/9789241595827_eng.pdf

Fuse Y, Ohashi Y, Yamaguchi S et al. Iodine status of pregnant and postpartum Japanese women: Effect of iodine intake on maternal and neonatal thyroid function in an iodine- sufficient area. J Clin Endocrinol Metab 2011;96(12):3846-54.

Pharoah PO, Buttfield IH, Hetzel BS. Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy. Lancet 1971;1(7694):308-10.

Kumar B, Moriarty H, Khan N et al. Progress in the Fijian iodine supplementation program. Network for sustained elimination of iodine deficiency (online). http://www.iodinenetwork.net/ documents/salt-sym-2009

Li M, McKelleher N, Moses T et al. Iodine nutritional status of children on the island of Tanna, Republic of Vanuatu. Public Health Nutr 2009;12(9):1512-8.

Zimmermann MB. Iodine deficiency in industrialized countries. Clin Endocrinol (Oxf) 2011;75(3):287-8.

Eastman CJ. Where has all our iodine gone? Med J Aust 1999;171(9):455-6.

Li M, Eastman CJ, Waite KV et al. Are Australian children iodine deficient? Results of the Australian National Iodine Nutrition Study. Med J Aust 2006;184(4):165-9.

Skeaff SA, Thomson CD, Gibson RS. Mild iodine deficiency in a sample of New Zealand schoolchildren. Eur J Clin Nutr 2002;56(12):1169-75.

Vanderpump MP, Lazarus JH, Smyth PP et al. Iodine status of UK schoolgirls: A cross-sectional survey. Lancet 2011;377(9782):2007-12.

Li M, Waite KV, Ma G et al. Declining iodine content of milk and re-emergence of iodine deficiency in Australia. Med J Aust 2006;184(6):307.

Eastman CJ, Jooste P. Current challenges in meeting global iodine requirements. In: Bhutta ZA, Hurrell RF, Rosenberg IH, eds. Meeting micronutrient requirements for health and development. Nestlé Nutrition Institute Workshop Series Volume 70. Basel: Karger, 2012.

WHO Secretariat, Andersson M, de Benoist B et al. Prevention and control of iodine deficiency in pregnant and lactating women and in children less than 2-years-old: Conclusions and recommendations of the Technical Consultation. Public Health Nutr 2007;10(12A):1606-11.

Li M, Liu DR, Qu CY et al. Endemic goitre in central China caused by excessive iodine intake. Lancet 1987;2(8553):257-9.

Konno N, Makita H, Yuri K et al. Association between dietary iodine intake and prevalence of subclinical hypothyroidism in the coastal regions of Japan. J Clin Endocrinol Metab 1994;78(2):393-7.

Published

2014-05-23

How to Cite

Eastman, C. J. (2014). Iodine Deficiency Disorders Continue to be a Problem in the Asia Pacific Region. Journal of the ASEAN Federation of Endocrine Societies, 27(2), 170. Retrieved from https://asean-endocrinejournal.org/index.php/JAFES/article/view/32

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Feature Articles