TY - JOUR AU - Mirasol, Roberto AU - Nicodemus Jr., Nemencio AU - Jain, Anand AU - Gadekar, Arvind Vilas AU - Yu-Gan, Susan PY - 2018/03/08 Y2 - 2024/03/29 TI - Self-Reported Hypoglycemia in Insulin-Treated Patients with Diabetes: Results from the Philippines Cohort of the International Operations Hypoglycemia Assessment Tool (IO HAT) Study JF - Journal of the ASEAN Federation of Endocrine Societies JA - J ASEAN Fed Endocr Soc VL - 33 IS - 1 SE - Original Articles DO - UR - https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/429 SP - 12 AB - <center><em><img src="https://asean-endocrinejournal.org/public/site/images/admin/va-2-md.jpg" alt="" width="618" height="309"></em></center><center><em><img src="https://asean-endocrinejournal.org/public/site/images/admin/va-2-lay.jpg" alt="" width="618" height="309"></em></center><center><em>*Visual Abstracts prepared by Dr. Monica Therese Cating-Cabral</em></center><p style="text-align: justify;"><strong>Objective.</strong> To determine the frequency of hypoglycemia in insulin-treated patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in the non-interventional International Operations Hypoglycemia Assessment Tool (IO HAT) study.</p><p style="text-align: justify;"><strong>Methodology.</strong>This sub-analysis included Filipino patients with T1DM or T2DM, aged 18 years and older, treated with insulin for more than 12 months, who completed the two-part self-assessment questionnaires (SAQ1 and SAQ2) and patient diaries that recorded hypoglycemia during retrospective (6 months/4 weeks before baseline) and prospective period (4 weeks after baseline) (ClinicalTrials.gov number: NCT02306681).</p><p style="text-align: justify;"><strong>Results.</strong> A total of 671 patients were enrolled and completed the SAQ1 (62 patients with T1DM and 609 patients with T2DM). Almost all patients (100% in T1DM and 99.3% in T2DM) experienced at least 1 hypoglycemic event prospectively. The incidence of any hypoglycemia was also high in the prospective period compared to retrospective period (72.6 [95% CI: 64.8, 80.9] events PPY and 43.6 [95% CI: 37.8, 49.9] events PPY; p=0.001, respectively) in T1DM patients.</p><p style="text-align: justify;"><strong>Conclusion.</strong> Among insulin-treated patients, higher rates of hypoglycemia were reported prospectively than retrospectively. This indicates that the patients in real-life setting often under report hypoglycemia. Patient education can help in accurate reporting and appropriate management of hypoglycemia and diabetes.</p> ER -