A Consensus of Key Opinion Leaders on the Management of Pre-diabetes in the Asia-Pacific Region


  • Roberto Mirasol St. Luke's Medical Center, Quezon City http://orcid.org/0000-0002-2468-1571
  • Ah Chuan Thai Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore
  • Aftab Ahmad Salahuddin Jinnah Teaching Hospital
  • Kathryn Tan Department of Medicine, University of Hong Kong
  • Chaicharn Deerochanawong Rajavithi Hospital, Rangsit University
  • Mafauzy Mohamed Universiti Sains Malaysia
  • Made Ratna Saraswati Division of Endocrinology and Metabolism, Sanglah General Hospital, Department of Internal Medicine, Faculty of Medicine, Udayana University, Denpasar, Bali
  • Bipin Kumar Sethi CARE Hospital, Hyderabad
  • Sanjiv Shah Nanavati Superspeciality Hospital, Mumbai
  • Nanny Natalia Soetedjo Division of Endocrinology and Metabolism, Hasan Sadikin General Hospital, Department of Internal Medicine, Faculty of Medicine, University of Pajajaran, Bandung
  • Swangjit Suraamornkul Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok
  • Rima Tan Institute for Studies on Diabetes Foundation, Inc.
  • Fareed Uddin National Institute of Diabetes and Endocrinology, Dow University of Health Sciences


impaired glucose tolerance, pre-diabetes, Asia


The Asia-Pacific region carries a high disease burden, with over half of the global diabetic population residing in this region. Increasing evidence shows that without targeted intervention, the progression from impaired glucose tolerance (IGT) to type 2 diabetes occurs more frequently in Asians compared with Caucasians. Furthermore, IGT is independently associated with an increased risk of cardiovascular disease, and should be managed as early as possible. Because diabetes is now a major public health issue, strategies aimed at prevention and treatment are urgently required. Lifestyle modification, including weight loss, dietary changes and increased physical activity, play a major role in controlling the disease. Significant evidence also supports the effectiveness of a combination of lifestyle modification and pharmacologic therapy, such as metformin, in delaying the onset of diabetes. Although the importance of lifestyle interventions is well recognized throughout Asia, many countries do not have formal recommendations to guide the diagnosis and management of individuals at risk of progression to diabetes. At a recent regional meeting, experts from the Asian region convened to develop consensus recommendations to guide clinicians in the management of Asian patients with pre-diabetes. These consensus recommendations provide a clear and concise approach to the management of individuals with IGT based on the available evidence and current best clinical practice.


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Author Biographies

Roberto Mirasol, St. Luke's Medical Center, Quezon City

Section Chief, Section of Endocrinology Diabetes and Metabolism

Ah Chuan Thai, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore

Associate Professor, Department of Medicine

Aftab Ahmad Salahuddin, Jinnah Teaching Hospital

Associate Professor of Medicine

Kathryn Tan, Department of Medicine, University of Hong Kong

Sir David Todd Professor in Medicine

Chaicharn Deerochanawong, Rajavithi Hospital, Rangsit University

Professor of Medicine

Mafauzy Mohamed, Universiti Sains Malaysia

Professor of Medicine

Made Ratna Saraswati, Division of Endocrinology and Metabolism, Sanglah General Hospital, Department of Internal Medicine, Faculty of Medicine, Udayana University, Denpasar, Bali

Internal Medicine Specialist, Consultant of Endocrinology, Metabolic disorder and Diabetes

Bipin Kumar Sethi, CARE Hospital, Hyderabad

Consultant Endocrinologist

Sanjiv Shah, Nanavati Superspeciality Hospital, Mumbai

Consultant Diabetologist & Endocrinologist

Nanny Natalia Soetedjo, Division of Endocrinology and Metabolism, Hasan Sadikin General Hospital, Department of Internal Medicine, Faculty of Medicine, University of Pajajaran, Bandung

Staff clinic in Endocrinology Division, Internal Medicine Department

Swangjit Suraamornkul, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok

Assistant Professor, Chief of Endocrinology Unit

Rima Tan, Institute for Studies on Diabetes Foundation, Inc.

Chief, Section of Diabetology

Fareed Uddin, National Institute of Diabetes and Endocrinology, Dow University of Health Sciences

Deputy Director  


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How to Cite

Mirasol, R., Thai, A. C., Salahuddin, A. A., Tan, K., Deerochanawong, C., Mohamed, M., Saraswati, M. R., Sethi, B. K., Shah, S., Soetedjo, N. N., Suraamornkul, S., Tan, R., & Uddin, F. (2017). A Consensus of Key Opinion Leaders on the Management of Pre-diabetes in the Asia-Pacific Region. Journal of the ASEAN Federation of Endocrine Societies, 32(1), 6. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/332



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