Management and Malignancy Rate of Thyroid Nodules with a Cytologic Diagnosis of Atypia or Follicular Lesion of Undetermined Significance

  • Armi Dianne Carlos Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St. Luke’s Medical Center, Quezon City, Philippines
  • Roberto Mirasol Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St. Luke’s Medical Center, Quezon City, Philippines
  • Eduardo Thomas Aquino Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St. Luke’s Medical Center, Quezon City, Philippines
  • Maria Lourdes Goco Department of Pathology, St. Luke’s Medical Center, Quezon City, Philippines
  • Pauline Rizelle Toledo Department of Radiology, St. Luke’s Medical Center, Quezon City, Philippines
  • Kevin Carl Santos School of Statistics, University of the Philippines, Diliman, Quezon City, Philippines

Abstract

Objective. This study describes the clinical data of adult patients who underwent Fine Needle Aspiration Biopsy (FNAB) of thyroid nodule(s) with a cytologic diagnosis of Atypia or Follicular Lesion of Undetermined Significance (AUS or FLUS) at St. Luke’s Medical Center from January 2012 to October 2013.

 

Methodology. Adult patients who underwent FNAB of the thyroid nodule with a cytologic diagnosis of AUS or FLUS were studied retrospectively using the ultrasound result, initial consultation form and operative techniques of these patients.  The cytologic and histopathologic diagnoses were retrieved through the electronic Healthcare-Results Management System.

 

Results and Conclusion.  A third (34%) of the patients with a cytologic diagnosis of AUS or FLUS (8.9%) underwent surgery.  Of the 68 patients who underwent surgery, 44 were benign and 24 were malignant with a malignancy rate of 35.3%.  Preoperatively, there were no ultrasound characteristics or microscopic descriptions significantly associated with malignancy.  The recommendation of the Bethesda System to do a repeat FNAB in these thyroid nodules should, therefore, be reconsidered.

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Published
2014-05-31
How to Cite
Carlos, A. D., Mirasol, R., Thomas Aquino, E., Lourdes Goco, M., Rizelle Toledo, P., & Carl Santos, K. (2014). Management and Malignancy Rate of Thyroid Nodules with a Cytologic Diagnosis of Atypia or Follicular Lesion of Undetermined Significance. Journal of the ASEAN Federation of Endocrine Societies, 29(1), 78. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/120
Section
Original Articles