THE MODIFIED FERRIMAN-GALLWEY SCORE AND HIRSUTISM AMONG FILIPINO WOMEN

Authors

  • Ma. Karen Celine Ilagan Section of Endocrinology, Diabetes, & Metabolism, The Medical City, Pasig City, Philippines
  • Elizabeth Paz-Pacheco Section of Endocrinology, Diabetes, & Metabolism, The Medical City, Pasig City, Philippines
  • Darwin Totesora Section of Endocrinology, Diabetes, & Metabolism, The Medical City, Pasig City, Philippines
  • Lyra Ruth Clemente-Chua Section of Gynecologic Ultrasound, Department of Obstetrics and Gynecology, The Medical City, Pasig City, Philippines
  • Jundelle Jalique Clinical and Translational Research Institute, The Medical City, Pasig City, Philippines

Keywords:

hirsutism, hyperandrogenism, modified Ferriman-Gallwey score

Abstract

INTRODUCTION
 The modified Ferriman-Gallwey (mFG) score is the gold standard in the clinical evaluation of hirsutism, a common manifestation of hyperandrogenism. Racial variations in terminal hair growth limit this tool. Ideally, race-specific mFG scores for hirsutism should be established. This study aimed to determine the mFG cut-off score among Filipino women and its association with biochemical hyperandrogenism.

METHODOLOGY
 A total of 128 Filipino females were included in this prospective cross-sectional study and divided into 2 groups: PCOS (n=28) and non-PCOS (n=100). Polycystic ovary syndrome (PCOS) was diagnosed using the 2003 Rotterdam Criteria while non-PCOS subjects were healthy controls conveniently sampled from the general population. They underwent mFG score determination, ovarian ultrasound by a single sonographer, and hormone testing. The mFG cut-off score was determined based on the 95th percentile in the non-PCOS group. Logistic regression was used to analyze the relationship of the determined mFG score with biochemical hyperandrogenism.

RESULTS
Normal values of the total mFG score is between 0 and 7. Using a cut-off score of 7, a higher proportion of hirsute women were observed in the PCOS group (17.9% vs. 5.0%, p=0.025). Elevated calculated free testosterone (cFT) was also significantly associated with hirsutism (odds ratio, 5.9; 95% CI, 1.4 – 23.8; p=0.013).

CONCLUSION
A score of 7 and above represents hirsute women in this population. Hirsute women are more likely to have elevated cFT.

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Published

2022-06-08

How to Cite

Ilagan, M. K. C., Paz-Pacheco, E., Totesora, D., Clemente-Chua, L. R., & Jalique, J. (2022). THE MODIFIED FERRIMAN-GALLWEY SCORE AND HIRSUTISM AMONG FILIPINO WOMEN. Journal of the ASEAN Federation of Endocrine Societies, 34(2), 48–49. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/2023

Issue

Vol. 34 No. 2 (2019): AFES Book of Abstracts (Supplement)

Section

Abstracts of Original Articles | General Endocrinology

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