The Lingering Battle of Persistent Hypoaldosteronism Following Adrenalectomy for Primary Aldosteronism:

A Case Report

Authors

  • Jie En Tan Sultanah Bahiyah Hospital, Ministry of Health, Malaysia https://orcid.org/0009-0005-2290-0987
  • Nor Shaffinaz Yusoff Azmi Merican Sultanah Bahiyah Hospital, Ministry of Health, Malaysia
  • Shartiyah Ismail Sultanah Bahiyah Hospital, Ministry of Health, Malaysia
  • Noor Rafhati Adyani Abdullah Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

DOI:

https://doi.org/10.15605/JAFES.041.01.5151

Keywords:

hypoaldosteronism, adrenalectomy, unilateral primary aldosteronism, hyperkalemia

Abstract

Persistent hypoaldosteronism post-adrenalectomy for unilateral primary aldosteronism is not uncommon and should be anticipated in patients with risk factors for development of such condition. Most cases of hypoaldosteronism post-adrenalectomy are transient. However, persistent hypoaldosteronism may occur as a result of delayed recovery of contralateral zona glomerulosa suppression, requiring mineralocorticoid replacement for the prevention or treatment of life-threatening hyperkalemia.

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Author Biographies

Jie En Tan, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Endocrine Unit, Department of Medicine, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Nor Shaffinaz Yusoff Azmi Merican, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Endocrine Unit, Department of Medicine, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Shartiyah Ismail, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Endocrine Unit, Department of Medicine, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Noor Rafhati Adyani Abdullah, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

Endocrine Unit, Department of Medicine, Sultanah Bahiyah Hospital, Ministry of Health, Malaysia

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Published

2026-04-27

How to Cite

Tan, J. E., Yusoff Azmi Merican, N. S., Ismail, S., & Abdullah, N. R. A. (2026). The Lingering Battle of Persistent Hypoaldosteronism Following Adrenalectomy for Primary Aldosteronism:: A Case Report. Journal of the ASEAN Federation of Endocrine Societies. https://doi.org/10.15605/JAFES.041.01.5151

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Section

Case Reports