Triple Synchronous Tumors Presenting as Right Nasolabial Basal Cell Carcinoma, Papillary Thyroid Carcinoma and Prolactinoma

A Rare Case Report


  • Mateo Te III Southern Philippines Medical Center, Davao City
  • Donnah Bless Lumanlan-Mosqueda Southern Philippines Medical Center, Davao City
  • Kenny Jun Demegillo Southern Philippines Medical Center, Davao City



multiple primary, synchronous tumors


Multiple primary tumors are rare, with a published meta-analysis that shows the frequency of second primary tumor at 3-5%, and a third tumor at 0.5%. A 57-year-old female sought consultation due to a persistently bleeding right nasolabial mass. On further history and examination, she also presented with a right anterior neck mass, repeated abortions, secondary amenorrhea, and loss of libido years prior. Serum prolactin was significantly elevated and an incidental finding of a pituitary mass on head and neck CT scan was appreciated. Metastasis and syndromic familial disorder were ruled out. Bromocriptine was given and she underwent total thyroidectomy and wide excision of the right nasolabial mass which turned out to be papillary thyroid carcinoma (PTC) and basal cell carcinoma (BCC) respectively on histopathologic report. On follow up, repeat serum prolactin decreased to normal levels. After extensive literature review, this is the first documented case of triple synchronous tumors with a combination of BCC of the right nasolabial area, PTC and prolactinoma in local, national and international studies. With comprehensive work up and literature search, the diagnosis was established and ultimately the patient benefited from a multidisciplinary management.


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Author Biographies

Mateo Te III, Southern Philippines Medical Center, Davao City

Senior Resident

Donnah Bless Lumanlan-Mosqueda, Southern Philippines Medical Center, Davao City

Professor, Department of Endocrinology

Kenny Jun Demegillo, Southern Philippines Medical Center, Davao City

Professor, Department of Oncology


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How to Cite

Te III, M. ., Lumanlan-Mosqueda, D. B., & Demegillo, K. J. . (2020). Triple Synchronous Tumors Presenting as Right Nasolabial Basal Cell Carcinoma, Papillary Thyroid Carcinoma and Prolactinoma: A Rare Case Report. Journal of the ASEAN Federation of Endocrine Societies, 35(2), 200–209.



Case Reports