Panhypopituitarism in a patient with Thalassemia Intermedia
DOI:
https://doi.org/10.15605/jafes.026.01.13Keywords:
panhypopituitarism, thalassemia intermediaAbstract
These are the magnetic resonance images (MRI) of the pituitary gland of a 37-year old male with β-thalassemia intermedia diagnosed at age 17, who was referred to the Endocrine clinic by his hematologist for evaluation of hypogonadism. He was on monthly blood transfusion between 2002 and 2007 and was started on iron chelation in 2003, with hemoglobin maintained between 8-9 g/dL. His condition was complicated by pancytopenia secondary to hypersplenism (for which he refused splenectomy) and secondary hemochromatosis affecting the liver and heartDownloads
References
Kushner, J.P., Porter, J.P. & Olivieri, N.F. Secondary iron overload. Hematology Am Soc Hematol Educ Program, 47-61 (2001).
Borgna-Pignatti, C., Marsella, M. & Zanforlin, N. The natural history of thalassemia intermedia. Ann N Y Acad Sci 1202, 214-20.
Gama, R., Smith, M.J., Wright, J. & Marks, V. Hypopituitarism in primary haemochromatosis; recovery after iron depletion. Postgrad Med J 71, 297-8 (1995)
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