Effect of Oral Calcium Supplementation on Lipid Profile and Atherogenic Index of Plasma

Authors

  • Mya Thanda Sein University of Medicine 2 Yangon
  • Tint Swe Latt University of Medicine 2 Yangon
  • Ohnmar - University of Medicine 2 Yangon

Keywords:

calcium supplementation, lipid profile, atherogenic index of plasma (AIP)

Abstract

*Visual Abstracts prepared by Dr. Monica Therese Cating-Cabral

Objective. To assess the effect of oral calcium supplementation on lipid profile and atherogenic index of plasma (AIP). 

Methodology. This study was undertaken in 28 centrally obese male subjects [age 26.4 (6.5) years], BMI 31.6 (4.7) kg/m2, WC 99.4 (6.4) cm. All participants received six tablets of CaCO(250 mg of elemental calcium/ capsule, for a total of 1500 md/day) for 8 weeks. Serum lipid profile including triglyceride, total cholesterol, HDL-C, LDL- C was measured at baseline and after intervention. AIP was calculated by using formula = log (TG/HDL-C).

Results. Oral calcium supplementation achieved a 22% (36 mg/dL, p<0.001) reduction in Triglyceride  from baseline [163.4 (37.9) mg/dL] and 19.2% ( 5.8 mg/dL, p<0.001) increase in HDL-C from baseline [30.4 (7.4) mg/dL)]. There were no significant treatment effects on total cholesterol [217.1 (41.21) mg/dL vs 196.3 (46.2) mg/dL] and LDL-C [155.4 (45.1) mg/dL vs 136.3 (45.1) mg/dL]. Significant reduction in serum total cholesterol and LDL-C level was only found in dyslipidemic centrally obese subjects. AIP decreased significantly by 51% with calcium carbonate treatment [median and interquartile range; 0.35 (0.29-0.44) vs 0.17 (0.04-0.44), p<0.01].

Conclusion. Eight-week calcium supplementation at 1500 mg/day led to a significant change in lipid levels and AIP.

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Author Biographies

Mya Thanda Sein, University of Medicine 2 Yangon

Associate Professor

Department of Physiology

Tint Swe Latt, University of Medicine 2 Yangon

Rector

Ohnmar -, University of Medicine 2 Yangon

Professor and Head

Department of Physiology

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Published

2014-11-29

How to Cite

Sein, M. T., Latt, T. S., & -, O. (2014). Effect of Oral Calcium Supplementation on Lipid Profile and Atherogenic Index of Plasma. Journal of the ASEAN Federation of Endocrine Societies, 29(2), 135. Retrieved from https://www.asean-endocrinejournal.org/index.php/JAFES/article/view/128

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