Cushingoid Features in an Obese Female with XY Karyotype
Abstract
Disorders of sexual development are congenital in nature. Complete androgen insensitivity syndrome (CAIS) is a rare disorder with an incidence of nearly 1 in 20,000 male births. The majority of patients present with complaints of primary amenorrhoea and are phenotypically female but genotypically male. We report a case of a 40-year-old female presenting with backache and skin ulcers who was found to have exogenous Cushing’s syndrome with long glucocorticoid administration and suspected CAIS. The ulcers were secondary to intramuscular pentazocine injections.
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References
Bista B, Beck N. Cushing syndrome. Indian J Pedatric. 2014;81:158-64.
http://dx.doi.org/10.1007/s12098-013-1203-8.
Clinician's Guide to prevention and treatment of osteoporosis.
http://emir.tums.ac.ir/upfiles/158936855.pdf. Accessed April 25, 2014.
Prasad HR, Khaitan BK, Ramam M, Sharma VK, Pandhi RK, Dhawan A, et al. Diagnostic clinical features of pentazocine induced ulcers. Int J Dermatol. 2005;44: 910-15. http://dx.doi.org/10.1111/j.1365-
2004.02291.x.
Kumar P, Jain M K. Gabapentin in the Management of Pentazocine Dependence: A Potent Analgesic - Anticraving Agent. JAPI. 2003;51: 673-76.
Khollova S, Hrdonkova E, Pomahacova R. Androgen insensitivity syndrome. Ceska Gynekol. 2014;79:38-42.
Hughes I A, Davies JD, Bunch TI, Pasterski V, Mastroyannopoulou K, Macdougall J. Androgen insensitivity syndrome. Lancet. 2012;380:1419-28. http://dx.doi.org/10.1016/S0140-6736(12)60071-3.
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