PRIMARY HYPERPARATHYROIDISM AND ITS DIFFERENT MANIFESTATIONS

A CASE SERIES AND LITERATURE REVIEW

Abstract

CASE
Primary hyperparathyroidism is an uncommon endocrine disorder occurring in 0.21 per 1000 people per year, usually diagnosed through an incidental elevation of serum calcium on routine laboratory workup. We report 3 cases of primary hyperparathyroidism in the Philippines and discuss the similarities and differences in their presentations, laboratory findings, and clinical course, 2 of whom underwent parathyroidectomy in St. Luke's Medical Center - Global City. These 3 cases come from different age groups, 2 female and 1 male, all presenting with different clinical symptoms prior to establishing the diagnosis. Two of these patients had their adenomas localized using 99mTc-sestamibi scanning, with the other patient through ultrasonography. Primary hyperparathyroidism remains an uncommon endocrine disorder and should be entertained when clinical symptoms can be related to an increase in serum calcium in any age group. This case series will add to the pool of data lacking in the Southeast Asian population.