PICWICKIAN SYNDROME, A RARE CASE AND DREADFUL COMPLICATION IN MORBID OBESITY

A CASE SERIES

Abstract

CASE
Picwickian Syndrome or Obesity hypoventilation syndrome (OHS) is a respiratory consequence of morbid obesity that is characterized by alveolar hypoventilation during sleep and wakefulness. The disorder involves a complex interaction between impaired respiratory mechanics, ventilatory drive, and sleep-disordered breathing. The first case: A 65-year-old female, from West Java Indonesia, with a BMI of 62.5 kg/m2, presented to the hospital with unconsciousness and respiratory distress. On admission, she was noted to have multiorgan dysfunction including respiratory failure and renal failure. She was diagnosed with Sepsis et causa Community-Acquired Pneumonia with MODS encephalopathy, morbid obesity with Picwickian syndrome, and tuberculosis. The second case: A 27-year-old male, from West Java Indonesia, with a BMI of 50.6 kg/m2. He came to the hospital with respiratory distress. He was diagnosed with Sepsis due to hospital-acquired pneumonia with MODS, respiratory failure, encephalopathy, morbid obesity with Pickwickian syndrome, hypokalemia, and exit site infection.